“The Vascular Dynamics Lab at McMaster University recognizes the importance of equity, diversity, and inclusion (EDI) efforts within our lab group and in welcoming and promoting members of black, Indigenous and people of colour (BIPOC) and other underrepresented communities in our research endeavours and collaborations …”. Please click here for more information on our lab’s EDI efforts.
In the Vascular Dynamics Lab we focus on examining the complex interactions of mechanical, neural and humoral factors in peripheral arteries in response to both acute and chronic changes in physical activity.
Alterations in blood vessel structure and function play essential roles in the responses of the cardiovascular system to physiological stresses by influencing several factors. For example, we know that chronic changes in an individual’s activity level can alter the vascular wall thickness, and mechanical properties (elasticity and compliance) and vascular responses to stress (capacity and rate of vasodilation or vasoconstriction). Little, however, is known about the discrete stimulus response characteristics of the mechanisms governing changes in vascular structure and function
Our contributions to date have included development and refinement of methodology for measurement of arterial compliance and endothelial function in humans and determining the impact of chronic activity (resistance, isometric, endurance and sprint interval training) or inactivity (immobilization) on arterial structure and function.
Our studies have yielded some important insights related to the possible labile nature and mechanistic measurement-dependence of some arterial adaptations. As such we conduct research in both healthy young populations and populations with elevated cardiovascular risk factors such as those with hypertension, coronary artery disease, congenital heart disease, cerebral palsy and spinal cord injury.